Color Health Services

Participant Engagement

Timely and informative communication with participants is important throughout the program lifecycle. Essential communication touch points include: recruitment, program education, consent, account activation, results delivery, scheduling of counseling sessions, and ongoing health guidance. Our elegant web platform provides custom program-specific landing pages, supports consent and patient data collection workflows, and scheduled interactions to engage participants at every phase of a population health program.

Clinical Services & Genetic Counseling

Genetic counselors are essential resources in ensuring genetic results are disclosed in a responsible way. Color’s board-certified genetic counselors can answer questions and help participants interpret their test results. Our clinical services team also works directly with physicians and care teams to ensure that results lead to actionable and relevant next steps.

Our genetic counseling team is extremely qualified and includes alumni of some of America’s most well-recognized genetic counseling programs like UCSF and Dana Farber. We use cutting edge, custom-designed software to support the genetic counseling process and automation of manual tasks such as scheduling, health history collection, and session documentation to achieve scale and efficiency without sacrificing quality.

Learn why the NIH chose Color to provide all genetic counseling services for the groundbreaking All of Us Research Program >


Genetic Testing and Sequencing

By combining lab automation and custom software with a deep knowledge of science, we offer one of the most accessible, clinical-grade genetic testing services available today. Color has an advanced, CAP-accredited and CLIA-certified laboratory that uses the newest technology, like acoustic liquid handlers and autonomous self-optimizing robotic systems that ensure the integrity of every sample.

Color generates sequence data with three primary goals: clinical-grade sequencing for clinically actionable genes, population-agnostic sequencing for statistical genetics, and raw sequencing data for desired option-value on future research or commercial applications. 

Color’s sequencing output includes both targeted panel data and whole genome sequencing (WGS) data. 

Read more about Color’s Genetic Sequencing capabilities in the Population Genomics Platform Playbook.

Return of Results

Color makes it easy and cost effective for research programs to return genetic results to the individual program participants. Our clinical infrastructure ensures that incidental findings are confirmed, clinically interpreted using best practices, and returned to participants and their physicians in clear language with support from our board-certified genetic counselors. Color was chosen by the National Institutes of Health (NIH) to return participant results for the million-person All of Us Research Program.

Color generates three sets of clinical reports based on the latest recommendations from professional health agencies and societies such as the CDC, ACMG, the U.S. Food and Drug Administration (FDA), and the Clinical Pharmacogenetics Implementation Consortium (CPIC).

Color Clinical Reports:

  • CDC Tier 1 genomic applications
  • ACMG secondary findings list
  • Pharmacogenomics

Read more about Color’s perspective on return of results for research participants and learn about our process and technology for returning participant results in the Population Genomics Platform Playbook.

Polygenic Scores (PRS)


Polygenic scores, also referred to as “polygenic risk scores” or “PRS,” measure the cumulative effect of many variants scattered across the genome. Each of these alone may have a very small contribution to risk—but in aggregate they can have a large effect. For institutions looking to build or apply polygenic scores, Color offers a complete and scalable solution.


Learn more about Color’s work with Polygenic Scores:

Low coverage whole genome sequencing enables accurate assessment of common variants and calculation of genome-wide polygenic scores
Genome Medicine (2019)

Polygenic risk is independent from the risk conferred by pathogenic variants in 12 known breast cancer genes
Presented by Color at the American College of Medical Genetics Conference (ACMG) 2019

Using low coverage sequencing for determining polygenic risk scores
Presented by Color at the American Society of Human Genetics Conference (ASHG) 2018

Personalized Care Routing

Actionable next steps are key to improving health outcomes. Color’s Personalized Care Routing integrates with an organization’s existing care or benefits ecosystem to guide participants to the most relevant programs available based on their comprehensive health assessments.

Care routing is done confidentially through the Color system and maintains all privacy protections on individual data. It is an effective way for employers, health systems, and other organizations to help individuals get access to the right programs, increase enrollment in key programs, and maximize the effectiveness of the entire health ecosystems.